Adderall IR (Instant Release) is a central nervous system stimulant commonly prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy. It can be taken in the form of an ingestible tablet or capsule and works by increasing alertness and focus. Understanding the Adderall half-life can help individuals who are taking this medication to understand how long it stays in their system.

Adderall Half Life

The half-life of Adderall IR is about 3 to 5 hours. That means that it takes 5 hours, on average, for the concentration of the medication in the blood to be reduced by half. This is an approximate figure and can vary depending on individual factors, such as hepatic function, renal function, and other medications taken.

Factors Affecting Adderall Half Life

The following are some of the individual factors that can affect how long Adderall IR stays in your system:

    • Age:</b > Adderall IR has a longer half life for elderly individuals and those whose bodies process medication more slowly.
    • Metabolic rate: People with higher metabolic rates tend to experience a shorter half life for Adderall IR.
    • Liver function: Adderall IR can take longer to be metabolized if the liver is not functioning properly.
    • Kidney function: The kidneys are involved in the metabolism of Adderall IR, so those with kidney dysfunction may experience an altered half life.


Once Adderall is taken, it is broken down into its metabolites, which are similarly active substances. The main metabolites are d-amphetamine and l-amphetamine, which have a half-life of 7 to 8 hours. They tend to stay in the system longer than the initial medication, and can be detected in urine tests for up to 3 days or longer, depending on the person’s metabolism.


The half life of Adderall IR can vary from person to person, but is generally 3 to 5 hours. To ensure safety and maximize the benefits of taking Adderall, it is important to understand how long it stays in your system and how it is metabolized.

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