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CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is a rare genetic disorder that can lead to stroke and other health problems. It is caused by a mutation in the NOTCH3 gene, which affects the structure and functioning of small and medium-sized blood vessels in the brain.

What are the Symptoms of CADASIL?

Patients with CADASIL may experience:

    • Headache
    • Difficulty speaking
    • Difficulty walking
    • Vision problems
    • Depression or personality changes
    • Memory loss

What is the Life Expectancy of Someone with CADASIL?

The life expectancy of someone with CADASIL is difficult to determine, as it depends on a variety of factors, such as age of onset, severity of symptoms, and the presence of other medical conditions. Generally, however, most people with CADASIL tend to live into their 60s. Unfortunately, some individuals may experience severe symptoms at an earlier age, leading to a shorter life expectancy.

It is important to note that CADASIL is a lifelong condition and cannot be cured. However, managing symptoms through lifestyle modifications and medical treatment can help to improve the quality of life and life expectancy of those affected.

Conclusion

CADASIL is a rare genetic disorder that affects the small and medium-sized blood vessels in the brain. While there is currently no cure for the condition, symptoms can be managed through lifestyle modifications and medical treatment. The life expectancy of someone with CADASIL can vary, but those affected generally tend to live into their 60s. Ultimately, early diagnosis and active management of the condition is key to improving the quality of life of those with CADASIL.

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